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Kalli Kappel

PhD Institution: Stanford University Cohort: 2020 Fellow

Kalli has used computational approaches to overcome experimental challenges to characterize a wide range of hitherto unresolved RNA-protein structures and to improve our understanding of some important biological processes, such as chromosome maintenance and RNA splicing. As a Schmidt Science Fellow, Kalli plans to employ high-throughput single-cell transcriptomics, cellular imaging, and computational modeling to explore the production of RNA-protein condensates. These are involved in some fundamental biological processes, but also in certain diseases, such as Huntington’s disease, which involve repetitive DNA sequences.