During her PhD, Elise studied how the critical cellular process of phosphorylation regulates health outcomes. She applied new mass spectrometry technologies and developed experimental and computational methods to identify the biological signals associated with glucose uptake.
As a Schmidt Science Fellow, Elise worked with Prof. Adam Butterworth at the University of Cambridge to pivot from biochemistry to computational genomics. Elise measures how genetic variants rewire our cellular machinery. She uses this approach to understand how specific genetic variants increase the risk of heart disease.
By linking disease risk genes to the druggable molecules in our bodies, Elise hopes to provide new opportunities for heart disease treatment and diagnosis. Elise will test the applicability of her findings in diverse populations to ensure her work will contribute to improving global health outcomes.